Thrombocytopenia as a Predictor of Mortality in Neonatal Pulmonary Haemorrhage: A Cohort Study from a Tertiary Hospital in Bangladesh
Sumaiya Liza
Registrar Department of Paediatrics Bangladesh Shishu Hospital & Institute Dhaka, Bangladesh Email:sumaiyaliza1510@gmail.com
Dite Talukder
Registrar Department of Paediatrics Bangladesh Shishu Hospital & Institute Bangladesh
Tapan Chandra Roy
Assistant Professor Department of Paediatrics Rangpur Community Medical College & Hospital Bangladesh
Md. Tanvir Hossain Khan
Resident Medical Officer Department of Paediatric Surgery Bangladesh Shishu Hospital & Institute Bangladesh
Keywords: Thrombocytopenia, neonatal pulmonary haemorrhage,
mortality, platelet count
Abstract
Background:
Neonatal pulmonary haemorrhage carries a high fatality risk, and simple
prognostic markers are crucial in low-resource environments.
Objective:
This study assessed whether thrombocytopenia predicts mortality
among affected neonates in a tertiary hospital in Bangladesh.
Methods:
A prospective cohort of seventy neonates with pulmonary haemorrhage,
admitted between July 2019 and June 2021, was evaluated. Platelet
counts were recorded at admission and monitored every 12 hours;
thrombocytopenia was defined as <150,000/µL. Mortality during
hospitalization served as the primary outcome.
Results:
Overall mortality reached 88.6%. Non-survivors had markedly lower
platelet levels than survivors, and this difference was statistically
significant. Regression analysis confirmed that thrombocytopenia is an
independent predictor of mortality. Survivors also exhibited an earlier
onset of haemorrhage compared with non-survivors.
Conclusion:
Routine platelet assessment provides a practical, accessible prognostic
measure and underscore the need for standardized transfusion and
monitoring strategies to improve survival.
J Rang Med Col. March 2026; Vol.11, No.1:153-158