Association of ACR with Serum Creatinine in Diabetic Patients in a Secondary Hospital of Bangladesh
Afroza Azad
Associate Professor Department of Clinical Biochemistry Lab BIHS General Hospital, Dhaka, Bangladesh Email: afrozaazad9@gmail.com
KM Istiak Rohan
Assistant Professor Department of Endocrinology Dhaka Medical College Hospital Dhaka, Bangladesh
Farah Imrana
Associate Professor Department of Pathology BIHS General Hospital Dhaka, Bangladesh
Keywords: Albumin-to-creatinine ratio, Serum creatinine, Diabetic
kidney disease, Renal function
Abstract
Background:
Albuminuria and serum creatinine are key markers of diabetic kidney
involvement, yet their relationship in routine secondary-care settings in
Bangladesh is not well characterized.
Objective:
This study aimed to evaluate the association between
albumin-to-creatinine ratio (ACR) and serum creatinine among diabetic
patients.
Methods:
This cross-sectional study was conducted among 70 diabetic patients at
Bangladesh Institute of Health Sciences (BIHS) General Hospital,
Dhaka, from July 2024 to June 2025. Spot urine ACR, serum creatinine,
fasting blood sugar, and post-breakfast blood sugar were analyzed using
standard cut-offs and appropriate comparative tests.
Results:
Mean ACR was 655.75±1023.99 mg/g, and mean serum creatinine was
1.32±0.49 mg/dL. Moderately increased ACR was observed in 50.0%
and severely increased ACR in 40.0%, while 44.3% had elevated
creatinine (>1.3 mg/dL). Although the ACR category was not
significantly associated with creatinine status (p=0.067), serum
creatinine rose significantly across ACR categories (p=0.001).
Glycaemic parameters showed no significant differences by creatinine
status.
Conclusion:
Routine ACR screening alongside creatinine may improve early DKD
detection in secondary care.
J Rang Med Col. March 2026; Vol.11, No.1:45-50
DOI: https://doi.org/10.3329/jrpmc.v11i1.89951